产品货号：
Z22540
中文名称：
OPTN抗体
英文名称：
Anti-OPTN Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-OPTN Antibody |
| 指标别名 | E3 14.7K interacting protein;FIP 2;FIP2;GLC1E;HIP 7;HIP7;Huntingtin yeast partner L;HYPL;NEMO related protein;NRP;optineurin;OPTN;TFIIIA INTP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | OPTN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Optineurin recombinant protein (Position:R241-I577).Human Optineurin shares 82% amino acid (aa) sequence identity with both mouse and rat Optineurin. |
| 实际分子量 | 70～75KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | OPTN is also known as NRP,FIP2 or HYPL.This gene encodes the coiled-coil containing protein optineurin.Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma.Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis,inflammation or vasoconstriction.Optineurin may also function in cellular morphogenesis and membrane trafficking,vesicle trafficking,and transcription activation through its interactions with the RAB8,huntingtin,and transcription factor IIIA proteins.Alternative splicing results in multiple transcript variants encoding the same protein. |
| Uniprot ID | Q96CV9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | optineurin |
| 蛋白名全称 | Optineurin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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